Platform Technologies

Platform Technologies

Eterna Therapeutics’ team of scientists and physicians are pioneers in using synthetic mRNA, cellular reprogramming, gene editing, and other cutting-edge technologies. Eterna Therapeutics’ mRNA Cell Engineering offers the theoretical ability to repair any cellular dysfunction. We plan to market a variety of therapeutics based on combining and refining the best attributes of these cutting-edge technologies.

Messenger RNA (mRNA) designates a special class of molecules containing instructions that determine how cells function. The same technology that helped create coronavirus vaccines can be used to treat other diseases by repairing disease-causing mutations and directing the formation of stem cells.

Eterna Therapeutics taps into the expertise of a number of partner companies, including Factor Bioscience, Exactis Biotherapeutics, MD Anderson, and the National University of Ireland, to aid in the research and development of mRNA gene-editing technology, mRNA delivery systems, and next-generation mRNA vaccines. Eterna Therapeutics is well on its way for the creation of a family of patent-protected mRNA-based therapeutics.

Synthetic mRNA

Messenger RNA (mRNA) carries the instructions contained in DNA to the cellular machinery that translates these instructions into functional proteins. Eterna makes mRNA with various chemical and structural enhancements (e.g., immuno-stealthing modifications, circular formats, etc.), and uses these molecules to improve cell function.

ToRNAdo™ mRNA Delivery

Eterna formulates mRNA using lipid nanoparticle (LNP) technology. The ToRNAdo™ delivery system surrounds and protects the mRNA cargo, enabling efficient delivery into human cells.

mRNA Gene Editing

Eterna uses mRNA to express gene editing proteins. These proteins are capable of deactivating, repairing, inserting, or replacing specific DNA sequences in living cells to repair genetic damage and confer new functionality to cells.

mRNA Cell Reprogramming

Eterna uses mRNA to express reprogramming proteins. These proteins re-write a cell’s gene expression program, enabling a somatic cell, such as a skin cell, to transform into another type of cell, such as a neuron or a stem cell. In one application of this technology, Eterna makes induced pluripotent stem (iPS) cells, a cell type that can differentiate into any needed cell.